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As a drug class the bisphosphonates have emerged in the past few years as the leading effective treatments for postmenopausal and other forms of osteoporosis.
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In addition, 186Re can be imaged, having a body distribution similar to that of 99mTc-methylene diphosphonate (MDP) on bone scans.
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OH)2D in thekidney, which, in turn, stimulates themobilization of Ca from bone andintestine and regulates the synthesis ofPTH by negative feedback.
Current therapy is closely linked to strategies for preventing disordered bone and mineral metabolism in advanced kidney disease and involves lowering the circulating levels of both phosphate and calcium.
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Lactating women need 2000 mg of calcium daily to prevent untimely catabolism of bone.
Content updates to the database include new FDA-approved drugs, new non-prescription and herbal therapies, newly published information regarding FDA label changes and relevant clinical studies affecting off-label utilization.
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