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Action mechanism of timolol to lower the intraocular pressure in rabbits. The results indicate that timolol reduces the rate of aqueous humor formation through reduction of blood flow to the ciliary process rather than via the inhibition of the active transport system or that of prostaglandin biosynthesis.
What produces aqueous Humour?
Aqueous humor is produced by the ciliary body and it flows (dashed line shown with arrowheads) from the posterior chamber through the pupil into the anterior chamber.
What does cupping of optic nerve mean?
The cupping of the optic nerve means the size of the depression in the middle of the nerve when viewed from the front of the eye. When there is damage to the optic nerve, the cupping increases.
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