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What is the alcohol disulfiram reaction? Disulfiram blocks this oxidation by inhibiting ALDH, causing a rapid rise of acetaldehyde in the blood when alcohol is consumed. The result is called a disulfiram - alcohol reaction, and it may increase the acetaldehyde concentration in blood to 5 to 10 times that occurring without disulfiram.
What happens if you drink on disulfiram? Don't drink alcohol while taking the drug or for up to 14 days after you stop taking it. When Antabuse is combined with alcohol, it may cause symptoms such as: Headache. Nausea or vomiting.
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