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It is postulated, but not proven, that the therapeutic effect of ketoconazole in tinea (pityriasis) versicolor is due to the reduction of Pityrosporum orbiculare ( Malassezia furfur) and that the therapeutic effect in dandruff is due to the reduction of Pityrosporum ovale.
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Ketoconazole (Nizoral, Extina, Xolegel, Kuric) is an anti-fungal medication prescribed to treat fungal infections such as thrush, ringworm, jock itch, athlete's foot, dandruff, tinea versicolor, blastomycosis, histoplasmosis, and coccidiomycosis.
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Successful response rates in the primary efficacy population for each of both three-day and single-day regimens of Ketoconazole Shampoo, 2%, were statistically significantly greater (73% and 69%, respectively) than a placebo regimen (5%).
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