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How long does fatigue last after cisplatin and etoposide treatments? Drugs such as vincristine, vinblastine, and cisplatin often cause CRF. Radiation therapy - Radiation therapy can cause cumulative fatigue (fatigue that increases over time). This can occur regardless of treatment site. CRF usually lasts from 3-4 weeks after treatment stops but can continue for up to 2-3 months.
How long does etoposide stay in your system? On intravenous administration, the disposition of Etoposide is best described as a biphasic process with a distribution half-life of about 1.5 hours and terminal elimination half-life ranging from 4 to 11 hours.
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